Poly-ADP ribosylation in health and disease. Led by Laura Lafon-Hughes.

Publications associated with this line of research

2021. Vilchez Larrea S, Valsecchi WM, Fernández Villamil SH (*), Lafon Hughes L(*).  First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cellsPeerJ 9:e11442 https://doi.org/10.7717/peerj.11442

2021. Lafon-Hughes, L., Fernández Villamil, S. (*), & Vilchez Larrea, S. (*). Tankyrase inhibitors hinder Trypanosoma cruzi infection by altering host-cell signalling pathways. Parasitology, 148(13), 1680-1690. doi:10.1017/S0031182021001402

2020. Perini V, Schacke M, Liddle P, Vilchez-Larrea S, Keszenman D J (*), Lafon-Hughes L(*). PARP Inhibitor Olaparib Causes No Potentiation of the Bleomycin Effect in VERO Cells, Even in the Presence of Pooled ATM, DNA-PK, and LigIV Inhibitors. International Journal of Molecular Sciences, Molecular Pharmacology section, Special Issue: Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach. Special Issue "Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach". Índice de impacto: 4.556 (Q1). https://www.mdpi.com/1422-0067/21/21/8288/pdf

2019. Schacke M. , Kumar J , Colwell N , Hermanson K , Folle G , Nechaev S , Dhasarathy A (*), Lafon Hughes, L (*). PARP-1/2 Inhibitor Olaparib Prevents or Partially Reverts EMT Induced by TGF-beta in NMuMG Cells. International journal of molecular sciences (Online), v.: 20 3 , p.:518. ISSN: 14220067. DOI: doi: 10.3390/ijms20030518.  Índice de impacto: 4.183 (2018); Cuartil Scimago: Q1 Índice de impacto: 2.353 (2018); Cuartil Scimago: Q1

2017. Lafon-Hughes L (*), Romeo C, Cal K, Vilchez Larrea SC, Sotelo Sosa J, Folle G, Fernández Villamil SH, Kun A (*). Poly(ADP-ribosylation) is present in murine sciatic nerve fibers and is altered in a Charcot-Marie-Tooth-1E neurodegenerative model. PeerJ. DOI: 10.7717/peerj.3318

2014. Lafon-Hughes L (*), Vilchez Larrea SC, Kun A, Fernández Villamil SH (*). VERO cells harbor a poly-ADP-ribose belt partnering their epithelial adhesion belt. PeerJ. DOI: 10.7717/peerj.617

(*): autor de correspondencia del trabajo

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