Publicaciones (Laboratorio de Epigenética e Inestabilidad Genómica)
Hernández P, Alem D, Nieves M, Cerecetto H, González M, Martínez-López W, Lavaggi ML. 2019. Chemosensitizer effect of cisplatin-treated bladder cancer cells by phenazine-5,10-dioxides. Environ Toxicol Pharmacol, 69:9-15. doi: 10.1016/j.etap.2019.03.015.
Pérez F, Varela M, Canclini L, Acosta S, Martínez-López W, López GV, Hernández P. 2019. Furoxans and tocopherol analogs-furoxan hybrids as anticancer agents. Anticancer Drugs, 30(4):330-338. doi: 10.1097/CAD.0000000000000721.
Kahl VFS, Dhillon V, Fenech M, de Souza MR, da Silva FN, Marroni NAP, Nunes EA, Cerchiaro G, Pedron T, Batista BL, Cappetta M, Martínez-López W, Simon D, da Silva J. 2018. Occupational Exposure to Pesticides in Tobacco Fields: The Integrated Evaluation of Nutritional Intake and Susceptibility on Genomic and Epigenetic Instability. Oxid Med Cell Longev. 7017423. doi: 10.1155/2018/7017423
Diego Luis Ribeiro, Heloisa Lizotti Ciliao, Ana Flávia Leal Specian, Juliana Mara Serpeloni, Marilesia Ferreira De Souza, Marcelo Marucci Pereira, Tangerina Wagner Vilegas, Paula Karina Boldrin, Flávia Aparecida Resende, Eliana Aparecida Varanda, Wilner Martínez-López, Miriam Sannomiya, Ilce Mara Syllos Cólus. 2018. Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential. Mutagenesis 2016 Mar 27;31(2):147-60. http://dx.doi.org/10.1093/mutage/gev066
Kahl VFS, Dhillon V, Simon D, da Silva F, Salvador M, Branco C, Cappetta M, Martinez-Lopez W, Thiesen F, Dias J, Souza C, Fenech M, da Silva J. 2017. Chronic occupational exposure endured by tobacco farmers from Brazil and association with DNA damage. Mutagenesis. 2018. 33(2):119-128. doi: 10.1093/mutage/gex045
Melissa Rosade Souza, Vivian Francilia Silva Kahl, Paula Rohr, Katia Kvitko, Monica Cappetta, Wilner Martínez-Lópes, Juliana da Silva. 2018. Shorter telomere length and DNA hypermethylation in peripheral blood cells of coal workers. Mutat Res Genet Toxicol Environ Mutagen. 2018. 836(Pt B):36-41. doi: 10.1016/j.mrgentox.2018.03.009.
Benedetti D, Lopes B, Souza C, Dias J, Niekraszewicz L, Capetta M, Martínez-López W, da Silva J. 2018. DNA damage and epigenetic alteration in soybean farmers exposed to complex mixture of pesticides. Mutagenesis. 24;33(1):87-95. doi: 10.1093/mutage/gex035.
Jaramillo-García V, Trindade C, Lima E, Guecheva TN, Villela I, Martinez-Lopez W, Corrêa DS, Ferraz ABF, Moura S, Quintana Sosa M, Da Silva J, Pegas Henriques JA. 2018. Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil. Journal of Ethnopharmacology. 213: 210-220. https://doi.org/10.1016/j.jep.2017.10.027
Marizcurrena JJ, Martínez-López W, Ma H, Lamparter T, Castro-Sowinski S. 2018. A highly efficient and cost‐effective recombinant production of a bacterial photolyase from the Antarctic isolate Hymenobacter sp. UV11. Extremophiles. doi: 10.1007/s00792-018-1059-y.
Ribeiro DL, Lizotti Ciliao H, Leal Specian AF, Serpeloni JM, De Oliveira MT, Varanda EA, Vilegas W, Saldanha LL, Martínez-López W, Dokkedal AL, Syllos Colus IM. 2018. Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro. Cytotechnology , 70(2): 713–728. doi: 10.1007/s10616-017-0173-5
Tuttis K, Serpeloni JM, Aparecida Varanda E, Campaner dos Santos L, Vilegas W, Martínez-Lopez W, de Syllos Cólus IM. 2018. Pouteria ramiflora (Mart.) Radlk. extract: Flavonoids quantification and chemopreventive effect on HepG2 cells. J Toxicol Environ Health A. 81(16):792-804. doi: 10.1080/15287394.2018.1491911.
Tassano M, Oddone N, Fernández M, Porcal W, García MF, Martínez-López W, J Benech JC, Cabral P. 2018. Evaluation of chromosomal aberrations induced by 188Re-dendrimer nanosystem on B16f1 melanoma cells. doi:10.1080/09553002.2018.1478161
Martínez-López W, Moreno-Ortega D, Valencia-Payan J, Sammader P, Meschini R, Palitti F. 2018. Influence of chromatin remodeling in the removal of UVC-induced damage in TCR proficient and deficient Chinese hamster cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis Volume 836, Part A, Pages 124-131. https://doi.org/10.1016/j.mrgentox.2018.08.003
Egidi A, Filippi S, Manganello F, Martínez-López W, Meschini R. 2018. Modulation of chromatin conformation by the histone deacetylase inhibitor trichostatin A promotes the removal of radiation-induced lesions in ataxia telangiectasia cell lines. Mutation Research/Genetic Toxicology and Environmental Mutagenesis Volume 836, Part A, Pages 109-116. https://doi.org/10.1016/j.mrgentox.2018.06.016
Martínez-López W. 2018. Preface to the Special Issue dedicated to the X Latin-American Congress of Environmental Mutagenesis, Carcinogenesis and Teratogenesis Association (X ALAMCTA Meeting). Mutation Research/Genetic Toxicology and Environmental Mutagenesis Volume 836, Part B, Page 1
Di Tomaso MV, Gregoire E, Martínez-López W. 2017. Effects of valproic acid on radiation-induced chromosomal aberrations in Human lymphocytes. Genome Integrity, 8: 4-9. doi:10.4103/2041-9414.198909
Marizcurrena JJ, Morel MA, Braña V, Morales D, Martinez-López W, Castro-Sowinski S. 2017. Searching for novel photolyases in UVC-resistant Antarctic bacteria. Extremophiles 21(2):409-418. doi: 10.1007/s00792-016-0914-y
Ana Flavia L. Specian, Diego L. Ribeiro, Juliana M. Serpeloni, Heloisa L. Ciliao, Wilner Martinez-Lopez, Katiuska Tuttis, Eliana A. Varanda, Wagner Vilegas, Ilce M. S. Colus. 2016. LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds. Cytotechnology 68:2729–2744. doi:10.1007/s10616-016-9998-6
O. García, M. Di Giorgio, A. Radl, M. R. Taja, C. E. Sapienza, M. M. Deminge, J. Fernández Rearte, M. Stuck Oliveira, P. Valdivia, A. I. Lamadrid, J. E. González, I. Romero, T. Mandina, C. Guerrero-Carbajal, C. Arceo Maldonado, G. E. Ramírez, M. Espinoza, W. Martínez-López and M. Di Tomasso. 2016. The Latin-American Biological Dosimetry Network (LBDNET). Radiation Protection Dosimetry Vol. 171, pp. 64-69. doi:10.1093/rpd/ncw209
Horst Romm, Christina Beinke, Omar Garcia, Marina Di Giorgio, Eric Gregoire, Gordon Livingston, David Lloyd, Wilner Martinez-Lopez, Jayne E. Moquet, Stephen L. Sugarman, Ruth C. Wilkins and Elizabeth A. Ainsbury. 2016. A new cytogenetic biodosimetry image repository for the dicentric assay. Radiation Protection Dosimetry , pp. 1–9. doi:10.1093/rpd/ncw158
Ursula Oestreicher, Daniel Samaga, Elizabeth Ainsbury, Ana Catarina Antunes, Ans Baeyens, Leonardo Barrios, Christina Beinke, Philip Beukes, William F. Blakely, Alexandra Cucu, Andrea De Amicis, Julie Depuydt, Stefania De Sanctis, Marina Di Giorgio, Katalin Dobos, Inmaculada Dominguez, Pham Ngoc Duy, Marco E. Espinoza, Farrah N. Flegal, Markus Figel, Omar Garcia, Octávia Monteiro Gil, Eric Gregoire, C. GuerreroCarbajal, İnci Güçlü, Valeria Hadjidekova, Prakash Hande, Ulrike Kulka, Jennifer Lemon, Carita Lindholm, Florigio Lista, Katalin Lumniczky, Wilner Martinez-Lopez, Nataliya Maznyk, Roberta Meschini, Radia M’kacher, Alegria Montoro, Jayne Moquet, Mercedes Moreno, Mihaela Noditi, Jelena Pajic, Analía Radl, Michelle Ricoul, Horst Romm, Laurence Roy, Laure Sabatier, Natividad Sebastià, Jacobus Slabbert, Sylwester Sommer, Monica Stuck Oliveira, Uma Subramanian, Yumiko Suto, Tran Que, Antonella Testa, Georgia Terzoudi, Anne Vral, Ruth Wilkins, Lusi Yanti Yanti, Demetre Zafiropoulos & Andrzej Wojcik. 2016. RENEB intercomparisons applying the conventional Dicentric Chromosome Assay (DCA). International Journal of Radiation Biology, pp. 1-12.
Beata Brzozowska, Elizabeth Ainsbury, Annelot Baert, Lindsay Beaton-Green, Lleonard Barrios, Joan Francesc Barquinero, Celine Bassinet, Christina Beinke, Anett Benedek, Philip Beukes, Emanuela Bortolin, Iwona Buraczewska, Christopher Burbidge, Andrea De Amicis, Cinzia De Angelis, Sara Della Monaca, Julie Depuydt, Stefania De Sanctis, Katalin Dobos, Mercedes Moreno Domene, Inmaculada Domınguez, Eva Facco, Paola Fattibene, Monika Frenzel, Octavia Monteiro Gil, Geraldine Gonon, Eric Gregoire, Ga€etan Gruel, Valeria Hadjidekova, Vasiliki I. Hatzi, Rositsa Hristova, Alicja Jaworska, Eniko} Kis, Maria Kowalska, Ulrike Kulka, Florigio Lista, Katalin Lumniczky, Wilner Martinez-Lopez, Roberta Meschini, Simone Moertl, Jayne Moquet, Mihaela Noditi, Ursula Oestreicher, Manuel Luis Orta Vazquez, Valentina Palma, Gabriel Pantelias, Alegria Montoro Pastor, Clarice Patrono, Laure Piqueret-Stephan, Maria Cristina Quattrini, Elisa Regalbuto, Michelle Ricoul, Sandrine Roch-Lefevre, Laurence Roy, Laure Sabatier, Lucia Sarchiapone, Natividad Sebastia, Sylwester Sommer, Mingzhu Sun, Yumiko Suto, Georgia Terzoudi, Francois Trompier, Anne Vral, Ruth Wilkins, Dimitros Zafiropoulos, Albrecht Wieser, Clemens Woda, and Andrzej Wojcik. 2016. RENEB accident simulation exercise. International Journal of Radiation Biology , pp.1-6.
Meschini R, Morucci E, Berni A, Martínez-López W, Palitti F. 2015. Role of chromatin structure modulation by the histone deacetylase inhibitor Trichostatin A on the radio-sensitivity of ataxia telangiectasia. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 777, 52–59. ISSN: 00275107; DOI: 10.1016/j.mrfmmm.2015.04.009.
Serpeloni JM, Leal Specian AF, Ribeiro DL, Tuttis K, Wagner Vilegas W, Martínez-López W, Dokkedal AL, Saldanha LL, De Syllos Cólus IM, Eliana Aparecida Varanda. 2015. Antimutagenicity and induction of antioxidant defense by flavonoid rich extract of Myrcia bella Cambess. in normal and tumor gastric cells. Journal of Ethnopharmacology 176, 345–355.
Ribeiro DL, Lizotti Cilião H, Leal Specian AF, Serpeloni JM, Ferreira De Souza M, Pereira Tangerina M, Vilegas W, Boldrin PK, Resende FA, Varanda EA, Martinez-López W, Sannomiya M, Cólus IM. 2015. Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential. Mutagenesis, p. 1-14. doi: 10.1093/mutage/gev066
Capítulos de libro
Fabiana Rey, Silvina Acosta, Wilner Martínez-López, Anaydeé Lena, Ana Acuña, Diana Miguez, Alejandro Ureta. 2016, Implementación de Métodos Moleculares y Microscópicos para Estudios Clínicos y Ambientales relativos a Cryptosporidium sp. en Uruguay. Innotec 12: 34-47. ISSN: 1688-3691.
Libros (redacción o edición)
Sharbel Weidner Maluf, Wilner Martínez-López, Juliana da Silva. 2018. Editorial "DNA Damage: Health and Longevity". Oxidative Medicine and Cellular Longevity, vol. 2018, Article ID 9701647, pp 1-2.
Edición del “Special Issue” titulado: “Latin-American Congress of Environmental Mutagenesis, Carcinogenesis and Teratogenesis Association (ALAMCTA)” Editors: Juliana Da Silva, Manoor Prakash Hande, Wilner Martínez-López. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 836, Part B, Pages 1-142 (December 2018). doi:10.1016/S1383-5718(18)30407-8