Publicaciones (Departamento de Genética)
2024
Reyes-Ábalos AL, Álvarez-Zabaleta M, Olivera-Bravo S, Di Tomaso MV. 2024. Astrocyte DNA damage and response upon acute exposure to ethanol and corticosterone. Frontiers in Neurotoxicology Vol 5:Article ID1277047.
Reyes-Ábalos LA, Álvarez-Zabaleta M, Olivera-Bravo S, Di Tomaso MV. 2024. Acute genetic damage induced by ethanol and corticosterone seems to modulate hippocampal astrocyte signaling. International Journal of Cell Biology Vol 2024, Article ID 5524487.
Anzibar Fialho, M., Martínez Barreiro, M., Vázquez Alberdi, L., Calero, M., Di Tomaso, M. V., Baranger, J., Tanter, M., Negreira, C., Rubido, N., Kun, A., & Brum, J. 2024. Functional ultrasound and brain connectivity reveal central nervous system compromise in Trembler-J mice, model of Charcot-Marie-Tooth disease. Cell Death & Differentiation, Springer Nature. Aceptado.
Mila R.; Hernández F.; Cordon, J.J.; Durán A.; Martínez-López W* 2024. Retrospective study of radiation exposures during interventional cardiology procedures performed at the University Cardiovascular Center of Uruguay. Brazillian Journal of Radiation Sciences, en prensa.
González Mesa, J. E., Alem, D., Valle Bourrouet, L., Chaves Campos, F. A., Ortíz Morales, F., Rodríguez González, M., Abarca Ramírez, M., Verdejo, V., Di Giorgio, M., Radl, A., Taja, M. R., Deminge, M., Rada-Tarifa, A., Lafuente-Alvarez, E., Farias de Lima, F., Hwang, S., Esposito Mendes, M., Mandina-Cardoso, T., Muñoz-Velastegui, G., Guerrero-Carbajal, Y. C., Arceo Maldonado, C., Monjagata, N., Aguilar-Coronel, S., Espinoza, M. E., Falcon de Vargas, A., Di Tomaso, M. V., Holladay, B., García Lima, O., & Martínez-López, W. 2024. LBDNet interlaboratory comparison for digitized image analysis of the dicentric chromosome assay and the application of differential weights for dose estimation. International Journal of Radiation Biology, 100(7):1019-1028.
Ikeda Kawasaki JA, Lucas Pinheiro LC, da Silva IM, Miqueloto CA, Brajão de Oliveira K, Ribeiro DL, Losi Guembarovski AFS, Terziotti F, Martinez-López W, Serpeloni JM, Losi Guembarovski R 2024. BCL-2 and γ-H2AX immunostaining profile in urothelial bladder cancer prognosis. Pathology - Research and Practice, Volume 264.
Pootheri A, Martínez-López W, Saraswathy R. 2024. A case-control study on asthma and obese patients: Influence of lifestyle patterns, serum trace elements, heavy metals, and total antioxidants. Heliyon. 10, e29270.
2023
Hochmann, J., Millán, M., Hernández, P., Lafon-Hughes, L., Aiuto, N., Silva, A., Llaguno, J., Alonso, J., Fernández, A., Pereira-Prado, V., Sotelo-Silveira, J., Bologna-Molina, R., & Arocena, M. (2023). Contributions of viral oncogenes of HPV-18 and hypoxia to oxidative stress and genetic damage in human keratinocytes. Scientific Reports.
Ruatta, S. M., Prada Gori, D. N., Fló Díaz, M., Lorenzelli, F., Perelmuter, K., Alberca, L. N., Bellera, C. L., Medeiros, A., López, G. V., Ingold, M., Porcal, W., Dibello, E., Ihnatenko, I., Kunick, C., Incerti, M., Luzardo, M., Colobbio, M., Ramos, J. C., Manta, E., Minini, L., Lavaggi, M. L., Hernández, P., Šarlauskas, J., Huerta García, C. S., Castillo, R., Hernández-Campos, A., Ribaudo, G., Zagotto, G., Carlucci, R., Medrán, N. S., Labadie, G. R., Martinez-Amezaga, M., Delpiccolo, C. M. L., Mata, E. G., Scarone, L., Posada, L., Serra, G., Calogeropoulou, T., Prousis, K., Detsi, A., Cabrera, M., Alvarez, G., Aicardo, A., Araújo, V., Chavarría, C., Mašič, L. P., Gantner, M. E., Llanos, M. A., Rodríguez, S., Gavernet, L., Park, S., Heo, J., Lee, H., Paul Park, K. H., Bollati-Fogolín, M., Pritsch, O., Shum, D., Talevi, A., & Comini, M. A. (2023). Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro. Frontiers in Pharmacology.
Varela, M., López, M., Ingold, M., Alem, D., Perini, V., Perelmuter, K., Bollati-Fogolín, M., López, G. V., & Hernández, P. (2023). New Nitric Oxide-Releasing Compounds as Promising Anti-Bladder Cancer Drugs. Biomedicines.
Ronco, A. L., Martínez-López, W., Calderón, J. M., Mintegui, G., & Storz, M. A. (2023). Dietary acid load and risk of cancer: new insights from a nationwide case-control study. World Cancer Research Journal, 10, e2547.
Keuchkerian, R., Suescun, L., Crisci, C., Aguiar, I., Martínez-López, W., Pérez Barthaburu, M. E., & Rodríguez Chialanza, M. (2023). Optimization of solvothermal experimental parameters to control the size of KMgF3 nanoparticles for photodynamic therapy. Applied Nanoscience. 2023 Jun 12:1-9.
Jansen van Vuuren, A., Bolcaen, J., Engelbrecht, M., Burger, W., De Kock, M., Durante, M., Fisher, R., Martínez-López, W., Miles, X., Rahiman, F., Tinganelli, W., & Vandevoorde, C. (2023). Establishment of Primary Adult Skin Fibroblast Cell Lines from African Savanna Elephants (Loxodonta africana). Animals, 13, 2353.
Mila, R., Hernandez, F., Cordon, J. J., Duran, A., & Martínez-López, W. (2023). Retrospective study of radiation exposures during interventional cardiology procedures performed at the University Cardiovascular Center of Uruguay. Brazilian Journal of Radiation Sciences.
2022
Acosta S, Canclini L, Marizcurrena JJ, Castro-Sowinski S, Hernández P. 2022. Photo-repair effect of a bacterial Antarctic CPD-photolyase on UVC-induced DNA lesions in human keratinocytes. Environ Toxicol Pharmacol. doi:10.1016/j.etap.2022.104001
DI TOMASO MV , Vázquez Alberdi L , Olsson D , Cancela S , Fernández A , Rosillo JC , Reyes Ábalos AL , Álvarez Zabaleta M , Calero M , Kun A. 2022. The PMP22 myelin protein and Lamin B1 colocalize in TrJ and Wt Schwann cell nuclei. Biomolecules. doi: 10.3390/biom12030456
Vázquez Alberdi L , Rosso G , Velóz L , Romeo C , Farias J , DI TOMASO MV , Calero M , Kun A. 2022. Curcumin and ethanol effects in Trembler-J Schwann cell culture. Biomolecules. doi: 10.3390/biom12040515.
Ronco AL, Martínez-López W, Calderón JM, Storz MA. 2022. Dietary acid load and esophageal cancer risk: A case-control study. Thorac Cancer. doi: 10.1111/1759-7714.14612.
Low GKM, Ting APL, Fok EDZ, Gopalakrishnan K, Zeegers D, Khaw AK, Jayapal M, Martínez-López W, Hande MP. 2022. Role of Xeroderma pigmentosum D (XPD) protein in genome maintenance in human cells under oxidative stress. Mutat Res Genet Toxicol Environ Mutagen. doi: 10.1016/j.mrgentox.2022.503444.
Joshua Paul, Anandi Shivaram, Panchami P, Bhumika Patel, Devi Jaikrishnan, Wilner Martínez-López, Radha Saraswathy. 2022. Awareness of Mobile Phone Radiation and Its Potential Health Hazards Among Students and Working-class Population During the COVID-19 Pandemic: A Cross-sectional Survey. Advanced Journal of Graduate Research. doi: https://doi.org/10.21467/ajgr.12.1.1-10
Diego Alem, Lucía Canclini, Susana Castro-Sowinski, Wilner Martínez-López. 2022. Chemosensitizer Effect of Violacein on Cisplatin-treated Bladder Cancer Cells. Clinical Complementary Medicine and Pharmacology. doi.org/10.1016/j.ccmp.2022.100036
Aswathi Pootheri, Wilner Martinez-Lopez and Radha Saraswathy. 2022. Action of Reactive Oxygen Species in Metabolic Diseases employed as Biomarkers of Oxidative Stress. Research Journal of Biotechnology. 17:207-215.
Ingold M, de la Sovera V, Dapueto R, Hernández P, Porcal W, López GV. 2022. Greener Synthesis of Antiproliferative Furoxans via Multicomponent Reactions. Molecules. doi:10.3390/molecules27061756
Laura Lafón. 2022. Poly(ADP-ribose), adherens junctions, vinculin and the actin cytoskeleton: current evidence, future perspectives and implications. BIOCELL. https://doi.org/10.32604/biocell.2022.022713
Ronco AL, Martínez-López W, Calderón JM, Storz MA. 2022. Dietary acid load and risk of head and neck and oral cavity cancers: An epidemiologic study. Oral Science Internaciontal. DOI: 10.1002/osi2.1150
Damián JP, Vázquez Alberdi L, Canclini L, Rosso G, Bravo SO, Martínez M, Uriarte N, Ruiz P, Calero M, Di Tomaso MV, Kun A. (2021). Central Alteration in Peripheral Neuropathy of Trembler-J Mice: Hippocampal pmp22 Expression and Behavioral Profile in Anxiety Tests. Biomolecules 11: 601. https:// doi.org/10.3390/biom11040601
Vilchez Larrea S, Valsecchi WM, Fernández Villamil SH (*), Lafon Hughes L(*). 2021. First body of evidence suggesting a role of a tankyrase-binding motif (TBM) of vinculin (VCL) in epithelial cells. PeerJ 9:e11442 https://doi.org/10.7717/peerj.11442
Lafon-Hughes, L., Fernández Villamil, S. (*), & Vilchez Larrea, S. (*). 2021. Tankyrase inhibitors hinder Trypanosoma cruzi infection by altering host-cell signalling pathways. Parasitology, 148 (13), 1680-1690. doi:10.1017/S0031182021001402
Acosta S, Canclini L, Galarraga C, Justet C, Alem D. 2021. Lab-made 3D printed stoppers as high-throughput cell migration screening tool. SLAS Technology, in press
Tuttis K, Maldonado Gomes da Costa DL, Serpeloni JM, Campaner dos Santos L, Varanda EA, Wagner V, Martínez-López W, de Syllos Colus IM. 2021. Phytochemical Profile, and Antiproliferative and Proapoptotic Effects of Pouteria ramiflora (Mart.) Radlk. Leaf Extract, and Its Synergism with Cisplatin in HepG2 Cells. Journal of Medicinal Food 24:1-12. https://doi.org/10.1089/jmf.2020.0045.
Rajagopalan A, Martinez-Lopez W, Saraswathy R. 2021. Cardiovascular Complications during COVID-19 Infection. Review Article J Clin Toxicol. 11. 473.
Ronco AL, Martínez-López W, Mendoza B, Calderón JM. 2021. Epidemiologic Evidence for Association between a High Dietary Acid Load and the Breast Cancer Risk (2021). Sci Medicine Journal, 3(2): 166-176. doi: 10.28991/SciMedJ-2021-0302-8
Hande V, Teo K, Srikanth P, Wong JSM, Sethu S, Martinez-Lopez W, Hande MP. 2021. Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts. Mutat Res. Jan-Feb;861-862:503303. doi: 10.1016/j.mrgentox.2020.503303.
Ronco AL, Martínez-López W, Calderón JM, Golomar W. 2021. Dietary acid load and lung cancer risk: A case-control study in men. Cancer Treat Res Commun. 28:100382. doi: 10.1016/j.ctarc.2021.100382.
Juliana Mara Serpeloni, Katiuska Tuttis, Ana Flavia Leal Specian, Diego Luis Ribeiro, Wilner Martínez-López, Silvia Cristina Heredia-Vieira, Wagner Vilegas, Eliana Aparecida Varanda, Ilce Mara de Syllos Colus. 2021. Selective anticancer effects of Serjania marginata Casar. Extract in gastric cells are mediated by antioxidant response. Environmental Toxicology, 36: 1544-1556. doi: 10.1002/tox.23151.
Ronco AL, M.A. Storz MA, Martínez-López W, J.M. Calderón JM, W. Golomar W. 2021. Dietary acid load and risk of kidney cancer: an epidemiologic case-control study. World Cancer Research Journal, 8: e2096. DOI: 10.32113/wcrj_20219_2096.
Ronco AL, M.A. Storz MA, Martínez-López W, J.M. Calderón JM, W. Golomar W. 2021. High dietary acid load is associated with prostate cancer risk: An epidemiological study. World Cancer Research Journal, 8: e2119. DOI: 10.32113/wcrj_202111_2119.
Nair, S., Cairncross, S., Miles, X., Engelbrecht, M., du Plessis, P., Bolcaen, J., Fisher, R., Ndimba, R., Cunningham, C., Martínez-López, W., Schunck, C., Vandevoorde, C. 2021. An Automated Microscopic Scoring Method for the γ-H2AX Foci Assay in Human Peripheral Blood Lymphocytes. JoVe. In press. DOI: 10.3791/62623.
Laura Lafon-Hughes. 2021. El Diario de Salto: ″Sprays nasales con polisacáridos: ¿barrera física anti-coronavirus?″
Perini V, Schacke M, Liddle P, Vilchez-Larrea S, Keszenman D J (*), Lafon-Hughes L(*). 2020. PARP Inhibitor Olaparib Causes No Potentiation of the Bleomycin Effect in VERO Cells, Even in the Presence of Pooled ATM, DNA-PK, and LigIV Inhibitors. International Journal of Molecular Sciences, Molecular Pharmacology section, Special Issue: Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach. Special Issue "Inhibition of DNA Repair Enzymes as a Valuable Pharmaceutical Approach". Índice de impacto: 4.556 (Q1). https://www.mdpi.com/1422-0067/21/21/8288/pdf
Schacke M, Kumar J, Colwell N, Hermanson K, Folle GA, Nechaev S, Dhasarathy A, Lafon-Hughes L. 2019. PARP-1/2 Inhibitor Olaparib Prevents or Partially Reverts EMT Induced by TGF- in NMuMG Cells. Int J Mol Sci 20:518. doi:10.3390/ijms20030518
Reyes-Ábalos AL, Liddle, P, Folle GA, Di Tomaso MV. 2018. γH2AX prefers late replicating metaphase chromosome regions. Mutat Res Genet Toxicol Environ Mutagen. 836(Pt B):114-121.
Gaiero P, Šimková H, Vrána J, Santiñaque FF, López-Carro B, Folle GA, van de Belt J, Peters SA, Doležel J, de Jong H. 2018. Intact DNA purified from flow-sorted nuclei unlocks the potential of next-generation genome mapping and assembly in Solanum species. MethodsX 5:328-336
Comentarios en revistas arbitradas
Folle GA. 2018. Chromosomes Forever. Prof. Máximo Eduardo Drets (1930-2017). Volume 836, Part B, Mutation Research/Genetic Toxicology and Environmental Mutagenesis 836 (Part B):2-3. https://doi.org/10.1016/j.mrgentox.2018.08.001
Capítulos de libros
Arun R. K. Kumar, Wilner Martínez-López, and Radha Saraswathy. 2022. Overall Thymoquinone pharmacological properties and its use as an anticancer agent. Chapter 8. Biotechnology for Toxic Remediation and Sustainability. Biotechnology for Toxic Remediation and Environmental Sustainability. ISBN 9781032319230